Caliciviruses ppt to pdf

Viral disease is a sum of the effects on the host of virus replication and of the immune response. A related strain, the ashington strain of rabbit calicivirus, was recovered from dead wild rabbits during an outbreak in europe. Powerpoint in pdf umwandeln kostenloses online tool. They are positivesense, singlestranded rna which is not segmented. They are icosahedral with 32 typical surface depressions that are sometimes described as hollows or cups from latin calyx, meaning cup. Click here to see an electron mircrograph image of caliciviruses. The family includes human rotaviruses, the most important cause of infantile gastroenteritis around the world figure 371. The results in table 1 indicate that the caliciviruses are inactivated at room temperature on surfaces and in solution after 7 days. Feline calicivirus or fcv for short is a viral condition that leads to flulike symptoms in the cat, and can present with varying degrees of severity. Noroviruses include a number of genetically related viruses, of which norwalk virus is the prototype. It is a fairly mild flulike condition and rarely causes serious complications. These symptoms emerge after an incubation time of 2 days and the symptoms only generally last for 3 days. Virus detection the presence of a virus in the in vitro assay can be detected by visible cellular changes cpe or hahd using red blood cells from different animal species, or combination thereof 28 days assay duration, or sooner if changes are noted. Feline calicivirus, a member of the genus vesivirus, causes respiratory disease in cats.

Presumptive diagnosis is based on clinical presentation. Feline panleukopenia feline panleukopenia updated september 17, 2015 the feline panleukopenia guidelines were. The cloning of norwalk virus and subsequently of other human caliciviruses has led to the development of. However, the inability to grow many of the cvs in cell culture, including the hucvs. Thirteen species are placed in this family, divided among eleven genera. Pdf rabbit haemorrhagic disease virus rhdv is a calicivirus of the genus lagovirus that causes rabbit haemorrhagic disease rhd in adult european.

In the powerpoint preferences dialog box, click general. Follow these instructions to set the print quality of the pdf. The crossing point cp was determined by use of the maximumsecondderivative function on the software. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Dhs national biodefense analysis and countermeasures centers nbacc is established as an essential, new approach to integrate national resources for homeland security, supporting public health, law enforcement, and national security. The demonstration of sequence relatedness between nv and other caliciviruses cvs, enabled by the cloning of the nv genome in 1990, was a major breakthrough that led to the widespread recognition of nv and other related small round structured viruses srsvs as members of the caliciviridae.

Research open access canine caliciviruses of four serotypes. Calicivirus volume 15, number 12december 2009 emerging. Members of the calicivirus family have 32 distinct, cupshaped surface depressions that give it a unique appearance. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Em is now mainly used for the diagnosis of viral gastroenteritis by detecting viruses in faeces e. Scmi calicivirus architecture scmi structure of feline calicivirus pdomain. May 04, 2010 diarrhea causing agents in world rotavirusinduced disease incidence is about the same in developed and developing countries. Feline calicivirus fcv is a virus that infects domestic cats, causing a range of flulike symptoms. The caliciviruses family caliciviridae are nonenveloped, positive sense, singlestranded rnaviruses with diameters ranging from 27 to 40 nm.

The 2008 version included more details in regard to cleaning specific equipment. The family caliciviridae includes a rapidly growing list of viruses that infect an. Through nextgeneration sequencing, many new astroviruses in. There are many strains of fcv with varying ability to infect cats and varying severity of disease. Ppt microbiologie des aliments powerpoint presentation. We conducted a descriptive study of age outbreaks reported to the public health agency of catalonia spain in 2010 and 2011. Infections in other hosts, for example sea lions, cats and primates appear to cause predominantly systemic and respiratory symptoms. Astroviruses infecting other species, particularly mammalian and avian, were identi. Reoviruses, rotaviruses, and caliciviruses jawetz, melnick. Human caliciviruses an overview sciencedirect topics. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Feline calicivirus is a virus that is an important cause of upper respiratory infections and oral disease in cats.

Scientific basis to assist department of homeland security dhs. Rabbit calicivirus disease rcd immunocontraception mechanical controlfencing harbour destruction shooting trapping chemical control fumigants poisoning efforts are aimed at integrated controls this means using a combination of conventional and new control methods to maximize the reduction of rabbit damage. Furthermore, critical issues on its survival and inactivation have been investigated making fcv a suitable surrogate for norovirus, enabling the evaluation of test agents11. The many strains of feline calicivirus fcv typically cause. Diagnosis of noncultivatable gastroenteritis viruses, the.

Characterization of a novel calicivirus causing systemic infection in. Structural insights into calicivirus attachment and entry david bhella tokyo medical and dental university july 1st 2019 mrc. Orf1 encodes the non structural ns polyprotein and the major capsid protein vp1. Members of other genera, norovirus and sapovirus, cause.

Caliciviruses cause a wide range of significant diseases in human and animals. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Taxonomy of the caliciviruses the journal of infectious. Inactivation of caliciviruses in suspension incubated for 30 min at 37. Ppt norovirus update 2008 powerpoint presentation free. Viral gastroenteritis is an intestinal infection where inflammation of the stomach and intestines occur from a virus.

Diagnosed by electron microscopy only, often difficult to. Use of inanimate environmental surfaces utilizing feline calicivirus as a surrogate virus for norovirus and virucidal efficacy of a disinfectant for use on inanimate environmental surfaces. Feline calicivirus fcv is a viral disease that affects cats and is commonly. Viral gastroenteritis is the second most common viral illness after upper respiratory tract infection. However, rhdv is an unusual calicivirus in that it has served also as an important model in the family caliciviridae by providing a range of beneficial outcomes as diverse as the creation of viruslike particles vlps for vaccine and therapeutics delivery, the elucidation of calicivirus replication and structural features at the molecular level, and the biological control of a vertebrate pest. Feline calicivirus infection advisory board on cat diseases. In developing countries, viral gastroenteritis is a major killer of infants who are undernourished. Since then naturally occurring recombinants have been detected for all four genera of the caliciviridae and has become an important mechanism in the emergence of new calicivirus variants. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Calicivirus infections commonly cause acute gastroenteritis, which is the inflammation of the stomach and intestines e.

Viral gastroenteritis argentina pdf ppt case reports. Majority of children have antibodies against caliciviruses by the age of three. Cats with a calicivirus infection often develop ulcers on the tongue, hard palate, gums, lips, or nose. Pdf converter is a online webbased document to pdf converter software. The crossing point cp was determined by use of the maximumsecond derivative function on the software. New names for two of the four genera of the caliciviridae were approved in 2002. Gastroenteritis an infection or inflammation of the digestive tract, particularly the stomach and intestines it is frequently referred to as the stomach or intestinal flu created by. The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the u.

Viral gastroenteritis it is thought that viruses are responsible for up to 34 of all infective diarrhoeas. Convert and create pdf from various types of files like word doc, excel xls, powerpoint ppt. Caliciviruses are ubiquitous and stable in the environment, providing a persistent source of infection. If it was a virus, then theres a really good chance that it. It seems that the maximum dissimilarity detected within the calicivirus pool is in the order of 30%5, and one study demonstrated that fcv255 and f9 have only 70% homology within region e of the capsid protein, which is a similar level of relatedness to that seen with other highly diverse strains including some of the highly virulent strains. It has a single structural protein characteristic of a calicivirus.

Genomic characterization of swine caliciviruses representing. Of the viruses that have been shown definitively to be causes of acute gastroenteritis, only the human caliciviruses cannot be grown in cell culture. The recent outbreaks have prompted an urgent need for a surrogate for norovirus8. Caliciviruses have a distinctive structure, sometimes described as a star of david, and are also distinctive in their size 27 to 35 nm, in having only a single major polypeptide, and in the functions of. Due to similarities in genome organization between the different genera, recombination predomoninantly occurs at the. Detection and molecular characterization of a canine.

Virus particles are detected and identified on the basis of morphology. Several caliciviruses are known to cause diseases in animal and man. Diagnostic methods in virology, laboratory diagnosis of. The caliciviruses are small, nonenveloped rna viruses that have characteristic cupshaped depressions on a spherical capsid surface. Gastroenteritis ppt free download as powerpoint presentation. Viral diarrhea free download as powerpoint presentation. Infants, children, immunocompromized patients and the elderly are most often affected by astrovrius infections. The study of rotaviruses, enteric adenoviruses, and astroviruses has been facilitated greatly by the ability to propagate these viruses in cell culture. Its nucleic acid contains singlestranded, positivesense rna. Norovirus and other caliciviruses global water pathogen. The name of these members of the caliciviridae family of nonenveloped rna viruses reflects their structure. Thus other rna viruses and coliphages that serve as surrogates for the human caliciviruses may best represent the efficiency of removal. Calicivirus definition of calicivirus by medical dictionary.

Feline calicivirus pronounced caleechee virus, also known as fcv, a common viral disease that affects cats, is characterized by upper respiratory symptoms, pneumonia, oral ulceration sores in the mouth, and occasionally arthritis. Like norwalk type viruses, vomiting is the prominent feature of disease. Properties of caliciviruses ssrna, positive sense, infectious, linear, monopartite genome. If youve ever gotten the stomach flu, theres a really good chance that what caused it was a virus. Unlike calicivirus infections in cats, caliciviruses are not regarded as important pathogens in dogs and are not usually included in diagnostic algorithms for canine infectious diseases. Save powerpoint presentations as pdf files office support. Calicivirus species and fecv straindifferences in inactivation are observed at this temperature range see section 3. Anesthetic equipment should be inspected, cleaned, and maintained on a schedule commensurate to surgery volume. Veterinary medical care guidelines for spayneuter programs.

Gastroenteritis is one of the most common illnesses of humans, and many different viruses have been causally associated with this disease. Scribd is the worlds largest social reading and publishing site. However, feline calicivirus fcv has been accepted as the model for evaluation of disinfectants against norovirus. Of those enteric viruses that have been established as etiologic agents of gastroenteritis, only the human caliciviruses cannot be cultivated in vitro. The name calicivirus comes from their characteristic star of david shape with cupshaped chalice indentations. Norovirus agent is an rna norovirus formerly norwalk virus taxonomic family caliciviridae that causes approximately 90% of epidemic nonbacterial outbreaks of gastroenteritis around the world, and may be responsible for 50% of all foodborne outbreaks of gastroenteritis in the us. Osmosis topic library become an osmosis prime member today and access over 1,200 videos with comprehensive coverage of pathology, physiology, pharmacology, and clinical reasoning topics. In this paper, an overview of caliciviruses is presented, with particular emphasis on the molecular aspects. Percentage of rotavirus infection in children under 5 years of age 6. All of the caliciviruses are singlestranded rna, nonenveloped viruses. To recognise an increase in illness from the reporting system is a slow way of discovering a waterborne outbreak. Human astroviruses hatvs are positivesense singlestranded rna viruses that were discovered in 1975.

Caliciviruses in swine viruses in three of the four established genera of the family caliciviridae have been detected in pigs sapovirus, norovirus and vesivirus, making this animal species of particular interest in the study of calicivirus pathogenesis and host range. Based on similar physicochemical and biologic properties, hev has been provisionally classified in the caliciviridae family. This chapter focuses on caliciviridae family whose member genuses are vesivirus, lagovirus, norovirus, sapovirus, and nebovirus. Caliciviruses because they belong to the virus family caliciviridae c. Please click here to download a pdf of the conference program. Pdf the viruses most commonly associated with food and waterborne outbreaks of gastroenteritis are the noroviruses. Based on the difference in morphology and the observa tion that. Hepatitis e virus and the safety of plasma products. They are icosahedral, with capsids the protein shell surrounding the viral nucleic acids composed of 32 capsomeres. Enteric caliciviruses from humanspreviously referred to as the norwalk family of viruses or small round structured viruses srsvs and hereinafter referred to as human calicivirusesnow appear to be candidate agents that could fill in a substantial portion of this diagnostic void. Apr 26, 2009 this study reports the molecular characterization of novel caliciviruses, the stvalerienlike viruses, which were isolated from pig feces in the province of quebec, canada between 2005 and 2007. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. These viral infections can often be prevented by frequent hand washing, and prompt disinfection of contaminated surfaces6, 7.

Recombination was first described in the human caliciviruses in 1997 hardy et al. Department of health and human services, the public health service, the centers for disease control and prevention, or the authors affiliated institutions. The caliciviruses, whose recognized members include vesicular exanthema of swine virus, feline calicivirus formerly feline picornavirus, and san miguel sea lion virus, were provisionally classified as a genus of the family picornaviridae melnick et al. Select the target conversion format, then upload up to 20 documents of supported input formats. The typical clinical signs of an upper respiratory infection involve the nose and throat such as sneezing, nasal congestion, conjunctivitis, and discharge from the nose or eyes. Under print quality paper pdf, set the desired quality to an option of your choice. Ppt norovirus update 2008 powerpoint presentation free to.

Their genetic information is encoded in a single strand of rna and they lack an envelope. Researchers for viral gastroenteritis in argentina includes institute of microbiology, biochemistry faculty, national university of tucuman, virology laboratory, central hospital of mendoza, viral gastroenteritis laboratory, department of virology, national institute of infectious diseases, national ministry of health and social action, institute of virology. Caliciviruses appear to have a predilection for the epithelium of the oral cavity and the deep tissues of the lungs. Caliciviruses have nonenveloped virions virus particles that are about 3539 nm 1 nm 10. But annual rotavirus diarrhea deaths are much greater in developing countries 8. The virions of this family are nonenveloped with icosahedral symmetry and are of 2740 nm in diameter by negativestain electron microscopy and 3540 nm by cryoelectron microscopy. Feline calicivirus fcv is a highly contagious pathogen with a widespread distribution in the feline population. Diagnosis cannot be solely based on clinical presentation. Sometimes people also have a lowgrade fever, chills, headache, muscle. Cases of acute gastroenteritis due to calicivirus in.

Parasitic infections disease and microbial agent sources of agent in water supply general symptoms transmission rash or itchy skin. What are the symptoms of illness caused by noroviruses. This infection may lead to watery diarrhoea, abdominal cramps, nausea or vomiting, and fever. The caliciviridae are a family of viruses, members of class iv of the baltimore scheme.

Thus other rna viruses and coliphages that serve as surrogates for the human caliciviruses may best represent. The cowden strain of porcine enteric calicivirus pec, a sapovirus, was. Treatment of an equal volume of cac717 with cell lysate infected with a nonenveloped virus, feline calicivirus fcv, reduced the tcid50. The genomes of stvalerienlike viruses contain 6409 nucleotides and include two main open reading frames orfs. No data are available on observable norovirus or caliciviruses removals by pit latrines, vault toilets or dry toilets, septic tanks, wetlands, aerated lagoons. Reoviruses are mediumsized viruses with a doublestranded, segmented rna genome. Caliciviruses are commonly encountered in contaminated food and water, and a large variety has been implicated as sources of infection during outbreak investigations.

Instantly convert text documents, presentations, spreadsheets and images to pdf format with this free online pdf converter. Leading edge of biodefense the national biodefense analysis. Viral pathogenesis this lecture will define and discuss the basic principles of viral pathogenesis, the entire process by which viruses cause disease. The symptoms of norovirus illness usually include nausea, vomiting, diarrhea, and some stomach cramping.

Norwalk virus and other caliciviruses medical microbiology. Norovirus and other caliciviruses global water pathogen project. Mlv, nonadjuvanted killed, adjuvantedi killed, nonadjuvanted intranasal mlv, nonadjuvanted begin as early as 6 weeks of age, then every 34 weeks until 16 weeks of age. Norwalk virus is a round, nonenveloped, 27nm virion that belongs to the caliciviridae family. The family caliciviridae contain small rna viruses that cause enteric disease in a wide variety of hosts including cattle, pigs, rabbits and humans. Calicivirus, any virus belonging to the family caliciviridae. Caliciviruses are nonenveloped, 27 to 40nm singlestranded rna viruses in the family caliciviridae. In the sixth report of the ictv, published in 1995 36, 37, all viruses in the caliciviridae were grouped into 1 genus, calicivirus, although it was apparent at that time that cvs were genetically and antigenically diverse and found in a broad range of hosts. Caliciviruses associated mainly with epidemic outbreaks of gastroenteritis, although occasionally responsible for endemic cases. Caliciviruses derive their name from the latin word for calix, or cup. Amongst them are vesicular exanthema virus of swine vesv, feline calicivirus, rabbit hemorrhagic disease virus rhdv, and norwalk and sapporolike viruses. Astroviruses are immunologically distinct from norwalk and other caliciviruses they belong to the family astroviridae.